![]() V d V t = P A C O 2 − P e C O 2 P A C O 2 Ī common step is to then presume that the partial pressure of carbon dioxide in the end-tidal exhaled air is in equilibrium with that gas' tension in the blood that leaves the alveolar capillaries of the lung. The original formulation by Bohr, required measurement of the alveolar partial pressure P A. The Bohr equation is used to quantify the ratio of physiological dead space to the total tidal volume, and gives an indication of the extent of wasted ventilation. Whereas Fowler visually partitioned phase II into two equal areas bordered by F(V), R(V), and VD, in the present. It differs from anatomical dead space as measured by Fowler's method as it includes alveolar dead space. According to Fowlers method, anatomical dead space (VD) can be determined graphically or computer-aided by iteration procedures by which phase III of a fraction-volume expirogram F(V) is back-extrapolated by a straight line R(V). airways but it may be measured non invasively by Fowler's method. This is given as a ratio of dead space to tidal volume. The sum of the anatomical and alveolar dead space is the physiological dead space. The Bohr equation, named after Danish physician Christian Bohr (1855–1911), describes the amount of physiological dead space in a person's lungs. Not to be confused with the Bohr model or the Bohr effect.
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